免疫球蛋白A1(IgA1)天然蛋白说明书
Native Immunoglobulin A1 (IgA1)
[ PROPERTIES ]
Host: Native
Source: Human
Subcellular Location: . Purity: >90%
Endotoxin Level: <1.0EU per 1μg (determined by the LAL method).
Formulation: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0,
containing 1mM EDTA, 1mM DTT, 0.01% sa rcosyl, 5% trehalose, and
preservative.
Applications: SDS-PAGE; WB; ELISA; IP.
(May be suitable for use in other assays to be determined by the end user.)
[ RELEVANCE ]
Immunoglobulin A (IgA, also referred to as sIgA) is an antibody that plays a criticalrole in mucosal immunity. More IgA is produced in mucosal linings than all othertypes of antibody combined; between three and five grams are secreted into theintestinal lumen each day. IgA exists in two isotypes, IgA1 and IgA2. They are bothheavily glycosylated proteins. While IgA1 predominates in serum (~80%), IgA2percentages are higher in secretions than in serum (~35% in secretions). IgA1 isthe predominant IgA subclass found in serum. Most lymphoid tissues have apredominance of IgA1-producing cells.
[ USAGE ]
Reconstitute in sterile ddH2O.
[ STORAGE AND STABILITY ]
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8ºC for one month.
Aliquot and store at -80ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37ºCfor 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is less
than 5% within the expiration date under appropriate storage condition.
本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用