TRIM25 polyclonal antibody
产品名称： TRIM25 polyclonal antibody
英文名称： TRIM25 polyclonal antibody
产品编号： PAB13293
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of TRIM25.
- Immunogen:
- A synthetic peptide corresponding to C-terminus 19 amino acids of human TRIM25.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Analysis of estrogen-responsive finger protein expression in benign and malignant human breast.
Thomson SD, Ali S, Pickles L, Taylor J, Pace PE, Lymboura M, Shousha S, Coombes RC.Int J Cancer. 2001 Jan 15;91(2):152-8.
- 2.
- Underdeveloped uterus and reduced estrogen responsiveness in mice with disruption of the estrogen-responsive finger protein gene, which is a direct target of estrogen receptor alpha.
Orimo A, Inoue S, Minowa O, Tominaga N, Tomioka Y, Sato M, Kuno J, Hiroi H, Shimizu Y, Suzuki M, Noda T, Muramatsu M.Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):12027-32.
- 3.
- Genomic binding-site cloning reveals an estrogen-responsive gene that encodes a RING finger protein.
Inoue S, Orimo A, Hosoi T, Kondo S, Toyoshima H, Kondo T, Ikegami A, Ouchi Y, Orimo H, Muramatsu M.Proc Natl Acad Sci U S A. 1993 Dec 1;90(23):11117-21.
- Entrez GeneID:
- 7706
- Protein Accession#:
- NP_005073
- Gene Name:
- TRIM25
- Gene Alias:
- EFP,RNF147,Z147,ZNF147
- Gene Description:
- tripartite motif-containing 25
- Omim ID:
- 600453
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. [provided by RefSeq
- Other Designations:
- estrogen-responsive finger protein,tripartite motif protein TRIM25,zinc finger protein 147 (estrogen-responsive finger protein),zinc finger protein-147
- Related Disease