IKBKG polyclonal antibody
产品名称： IKBKG polyclonal antibody
英文名称： IKBKG polyclonal antibody
产品编号： PAB24870
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of IKBKG.
- Immunogen:
- A synthetic peptide corresponding to IKBKG.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 43
- Reactivity:
- Human
- Specificity:
- IKBKG polyclonal antibody detects endogenous levels of IKBKG protein.
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 1 mg/mL
- Purity:
- > 95% by SDS-PAGE
- Storage Buffer:
- In 1x PBS, pH 7.2 (0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of HepG2 cell lysate with IKBKG polyclonal antibody (Cat # PAB24870).
- Entrez GeneID:
- 8517
- Gene Name:
- IKBKG
- Gene Alias:
- AMCBX1,FIP-3,FIP3,Fip3p,IKK-gamma,IP,IP1,IP2,IPD2,NEMO
- Gene Description:
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [supplied by RefSeq
- Other Designations:
- NFkappaB essential modulator,OTTHUMP00000026027,OTTHUMP00000026028,OTTHUMP00000026029,incontinentia pigmenti
- Gene Pathway
- Acute myeloid leukemia
- Adipocytokine signaling pathway
- Apoptosis
- B cell receptor signaling pathway
- Chemokine signaling pathway
- Chronic myeloid leukemia
- Epithelial cell signaling in Helicobacter pylori infection
- MAPK signaling pathway
- Pancreatic cancer
- Pathways in cancer
- Primary immunodeficiency
- Prostate cancer
- Small cell lung cancer
- T cell receptor signaling pathway
- Toll-like receptor signaling pathway