PDF purified MaxPab mouse polyclonal antibody (B01P)
产品名称： PDF purified MaxPab mouse polyclonal antibody (B01P)
英文名称： PDF purified MaxPab mouse polyclonal antibody (B01P)
产品编号： H00064146-B01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human PDF protein.
- Immunogen:
- PDF (AAH19912.1, 1 a.a. ~ 243 a.a) full-length human protein.
- Sequence:
- MARLWGALSLRPLWAAVPWGGAAAVGVRACSSTAAPDGVEGPALRRSYWRHLRRLVLGPPEPPFSHVCQVGDPVLRGVAAPVERAQLGGPELQRLTQRLVQVMRRRRCVGLSAPQLGVPRQVLALELPEALCRECPPRQRALRQMEPFPLRVFVNPSLRVLDSRLVTFPEGCESVAGFLACVPRFQAVQISGLDPNGEQVVWQASGWAARIIQHEMDHLQGCLFIDKMDSRTFTNVYWMKVND
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of PDF expression in transfected 293T cell line (H00064146-T02) by PDF MaxPab polyclonal antibody.
Lane 1: PDF transfected lysate(26.73 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 64146
- GeneBank Accession#:
- BC019912
- Protein Accession#:
- AAH19912.1
- Gene Name:
- Gene Alias:
- -
- Gene Description:
- peptide deformylase (mitochondrial)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells. [provided by RefSeq
- Other Designations:
- peptide deformylase,peptide deformylase-like protein
- Related Disease