HAT1 polyclonal antibody
产品名称： HAT1 polyclonal antibody
英文名称： HAT1 polyclonal antibody
产品编号： PAB2245
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of HAT1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human HAT1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Control of Smad7 stability by competition between acetylation and ubiquitination.
Gronroos E, Hellman U, Heldin CH, Ericsson J.Mol Cell. 2002 Sep;10(3):483-93.
- 2.
- Effects of acetylation of histone H4 at lysines 8 and 16 on activity of the Hat1 histone acetyltransferase.
Makowski AM, Dutnall RN, Annunziato AT.J Biol Chem. 2001 Nov 23;276(47):43499-502. Epub 2001 Oct 3.
- 3.
- Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation.
Cheung P, Tanner KG, Cheung WL, Sassone-Corsi P, Denu JM, Allis CD.Mol Cell. 2000 Jun;5(6):905-15.
- Entrez GeneID:
- 8520
- Protein Accession#:
- NP_003633;O14929
- Gene Name:
- HAT1
- Gene Alias:
- KAT1
- Gene Description:
- histone acetyltransferase 1
- Omim ID:
- 603053
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq
- Other Designations:
- -