USP21 polyclonal antibody
产品名称： USP21 polyclonal antibody
英文名称： USP21 polyclonal antibody
产品编号： PAB1834
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of USP21.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human USP21.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Human and mouse proteases: a comparative genomic approach.
Puente XS, Sanchez LM, Overall CM, Lopez-Otin C.Nat Rev Genet. 2003 Jul;4(7):544-58.
- 2.
- Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins.
Gong L, Kamitani T, Millas S, Yeh ET.J Biol Chem. 2000 May 12;275(19):14212-6.
- 3.
- Generation and analysis of 280,000 human expressed sequence tags.
Hillier LD, Lennon G, Becker M, Bonaldo MF, Chiapelli B, Chissoe S, Dietrich N, DuBuque T, Favello A, Gish W, Hawkins M, Hultman M, Kucaba T, Lacy M, Le M, Le N, Mardis E, Moore B, Morris M, Parsons J, Prange C, Rifkin L, Rohlfing T, Schellenberg K, Bento Soares M, Tan F, Thierry-Meg J, Trevaskis E, Underwood K, Wohldman P, Waterston R, Wilson R, Marra M.Genome Res. 1996 Sep;6(9):807-28.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of HeLa cell lysate (35 ug/lane) with USP21 polyclonal antibody (Cat # PAB1834).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with USP21 polyclonal antibody (Cat # PAB1834), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 27005
- Protein Accession#:
- NP_036607;Q9UK80
- Gene Name:
- USP21
- Gene Alias:
- MGC3394,USP16,USP23
- Gene Description:
- ubiquitin specific peptidase 21
- Omim ID:
- 604729
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants have been described. [provided by RefSeq
- Other Designations:
- NEDD8-specific protease,deubiquitinating enzyme 21,ubiquitin carboxyl-terminal hydrolase 21,ubiquitin specific protease 21,ubiquitin thiolesterase 21,ubiquitin-specific processing protease 21,ubiquitin-specific protease 16,ubiquitin-specific protease 21