ELK1 (phospho S389) polyclonal antibody
产品名称： ELK1 (phospho S389) polyclonal antibody
英文名称： ELK1 (phospho S389) polyclonal antibody
产品编号： PAB0460
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of ELK1.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S389 of human ELK1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- SUMOylation regulates nucleo-cytoplasmic shuttling of Elk-1.
Salinas S, Briancon-Marjollet A, Bossis G, Lopez MA, Piechaczyk M, Jariel-Encontre I, Debant A, Hipskind RA.J Cell Biol. 2004 Jun 21;165(6):767-73.
- 2.
- Dynamic interplay of the SUMO and ERK pathways in regulating Elk-1 transcriptional activity.
Yang SH, Jaffray E, Hay RT, Sharrocks AD.Mol Cell. 2003 Jul;12(1):63-74.
- 3.
- Immediate-early gene induction by the stresses anisomycin and arsenite in human osteosarcoma cells involves MAPK cascade signaling to Elk-1, CREB and SRF.
Bebien M, Salinas S, Becamel C, Richard V, Linares L, Hipskind RA.Oncogene. 2003 Mar 27;22(12):1836-47.
- Applications
- Entrez GeneID:
- 2002
- Protein Accession#:
- NP_005220;P19419
- Gene Name:
- ELK1
- Gene Alias:
- -
- Gene Description:
- ELK1, member of ETS oncogene family
- Omim ID:
- 311040
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
- Other Designations:
- ELK1 protein,OTTHUMP00000023224,OTTHUMP00000023225
- Related Disease