Product Information
    
 
    

    

        

            

                

                
Product Name
                
                

                
Cat#
                
                

                
Size
                
                

                
Price（¥）
                
            
            

                

                
Recombinant Rat Epidermal Growth Factor(Rat EGF)
                
                

                
92705ES60
                
                

                
100 μg
                
                

                
1855.00
                
            
            

                

                
92705ES76
                
                

                
500 μg
                
                

                
7495.00
                
            
        
    
    
    
 
    
Product Description
    
 
    
Epidermal Growth Factor (EGF) is a small growth factor containing 53 amino acid residues capable of stimulating the proliferation of both mesenchymal and epithelial cells. The mature protein is much smaller, only 53 aa, and is generated by proteolytic cleavage of the EGF domain proximal to the transmembrane region. EGF is well conserved across mammals with mature human EGF 70% identical to mature mouse and rat EGF. EGF and fibroblast growth factor 2 (FGF-2) induce the proliferation of neural precursor cells isolated from specific regions of the embryonic and adult brain. EGF and somatomedin C-supplemented medium was shown to be capable of replacing the progression activity of 5% platelet-poor plasma (PPP) for competent density-inhibited BALB/c-3T3 cells. Biological activities ascribed to EGF include epithelial development, angiogenesis, inhibition of gastric acid secretion, fibroblast proliferation, and colony formation of epidermal cells in culture.
    
 
    
Product Properties
    
 
    

    

        

            

                

                
Synonyms
                
                

                
beta-urogastrone, EGF, epidermal growth factor, hEGF, HOMG4, URG, Urogastrone
                
            
            

                

                
Accession
                
                

                
P07522
                
            
            

                

                
GeneID
                
                

                
25313
                
            
            

                

                
Source
                
                

                
E.coli-derived rat EGF, Asn974-Arg1026.
                
            
            

                

                
Molecular Weight
                
                

                
Approximately 6.1 kDa.
                
            
            

                

                
AA Sequence
                
                

                
NSNTGCPPSY DGYCLNGGVC MYVESVDRYV CNCVIGYIGE RCQHRDLRWW KLR
                
            
            

                

                
Tag
                
                

                
None
                
            
            

                

                
Physical Appearance
                
                

                
Sterile Filtered White lyophilized (freeze-dried) powder.
                
            
            

                

                
Purity
                
                

                
>97% by SDS-PAGE and HPLC analyses.
                
            
            

                

                
Biological Activity