CASP6 (Human) Recombinant Protein (Q01)
产品名称: CASP6 (Human) Recombinant Protein (Q01)
英文名称: CASP6 (Human) Recombinant Protein (Q01)
产品编号: H00000839-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human CASP6 partial ORF ( NP_001217, 26 a.a. - 125 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- YKREMFDPAEKYKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRDNLTRRFSDLGFEVKCFNDLKAEELLLKIHEVSTVSHADADCFVCVFLSHGEGN
- Theoretical MW (kDa):
- 36.74
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 839
- GeneBank Accession#:
- NM_001226
- Protein Accession#:
- NP_001217
- Gene Name:
- CASP6
- Gene Alias:
- MCH2
- Gene Description:
- caspase 6, apoptosis-related cysteine peptidase
- Omim ID:
- 601532
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq
- Other Designations:
- apoptotic protease MCH-2,caspase 6,caspase 6, apoptosis-related cysteine protease
- Interactome
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Alcoholism
- Carcinoma, Large Cell
- Colorectal Neoplasms
- Disease Progression
- Gastrointestinal Stromal Tumors
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hodgkin Disease
- Lung Neoplasms
- Lymphatic Metastasis
- Lymphoma, Non-Hodgkin
- Lymphoproliferative Disorders
- Neoplasm Metastasis
- Neoplasms, Squamous Cell
- Occupational Diseases
- Prostatic Neoplasms
- Small Cell Lung Carcinoma
- Stomach Neoplasms