F12 polyclonal antibody (Biotin)-抗体-抗体-生物在线
亚诺法生技股份有限公司（Abnova)
F12 polyclonal antibody (Biotin)

F12 polyclonal antibody (Biotin)

商家询价

产品名称： F12 polyclonal antibody (Biotin)

英文名称： F12 polyclonal antibody (Biotin)

产品编号： PAB19923

产品价格： null

产品产地： 台湾

品牌商标： Abnova

更新时间： null

使用范围：

亚诺法生技股份有限公司（Abnova)
  • 联系人 :
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  • 邮编 : 11493
  • 所在区域 : 台湾
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  • 邮箱 : sales@abnova.com.tw
进入展台

  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against native F12.
  • Immunogen:
  • Native purified F12 from human plasma.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Conjugation:
  • Biotin
  • Purification:
  • Affinity purification
  • Storage Buffer:
  • In PBS, pH 7.5 (0.02% sodium azide, 50% glycerol (v/v))
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Enzyme Immunoassay
  • Application Image
  • Western Blot
  • Enzyme Immunoassay
  • Gene Information
  • Entrez GeneID:
  • 2161
  • Gene Name:
  • F12
  • Gene Alias:
  • HAE3,HAEX,HAF
  • Gene Description:
  • coagulation factor XII (Hageman factor)
  • Gene Summary:
  • This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged. [provided by RefSeq
  • Other Designations:
  • Hageman factor,coagulation factor XII
  • Interactome

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