Caspase-1 Assay Kit (Colorimetric)
产品名称: Caspase-1 Assay Kit (Colorimetric)
英文名称: Caspase-1 Assay Kit (Colorimetric)
产品编号: KA0727
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Caspase-1 Assay Kit (Colorimetric) is used for detecting the activity of caspases that recognize the sequence YVAD using colorimetric method.
- Reactivity:
- Mammals
- Storage Instruction:
- Store the kit at -20°C.
- Protocol:
- Protocol Download
- MSDS:
- Download
- Suitable Sample:
- Cell Lysate, Tissue Lysate
- Detection Method:
- Colorimetric
- Regulation Status:
- For research use only (RUO)
- Application Image
- Functional Study
- Entrez GeneID:
- 834
- Gene Name:
- CASP1
- Gene Alias:
- ICE,IL1BC,P45
- Gene Description:
- caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
- Omim ID:
- 147678
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms. [provided by RefSeq
- Other Designations:
- CASP1 nirs variant 1,IL1B-convertase,caspase 1,caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase),interleukin 1-B converting enzyme,interleukin 1-beta convertase
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Alzheimer Disease
- Asthma
- Asthma
- Bronchiolitis, Viral
- Cardiovascular Diseases
- Cognition
- Coronary Artery Disease
- Diabetes Mellitus, Type 2
- Disease Susceptibility
- Edema
- Gastrointestinal Stromal Tumors
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hodgkin Disease
- Infant, Premature, Diseases
- Inflammation
- Leukemia, chronic myeloid
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive