Product Information
    
 
    

    

        

            

                

                
Product Name
                
                

                
Cat#
                
                

                
Size
                
                

                
Price（¥）
                
            
            

                

                
Recombinant Mouse Fibroblast growth factor 8
                
(Mouse FGF-8)
                
                

                
91317ES08
                
                

                
5 μg
                
                

                
815.00
                
            
            

                

                
91317ES60
                
                

                
100 μg
                
                

                
7865.00
                
            
            

                

                
91317ES76
                
                

                
500 μg
                
                

                
20425.00
                
            
        
    
    
    
 
    
Product Description
    
 
    
Fgf-8 is a member of the fibroblast growth factor (FGF) family that was initially identified as an androgen-inducible growth factor in a mammary carcinoma cell line. Fgf-8 is one of the key signaling molecules implicated in the initiation, outgrowth, and patterning of vertebrate limbs. The cloned 1.26-kb cDNA contained an open reading frame encoding 212 amino acid residues with 84%, 86%, and 80% amino acid identities to those of Xenopus, chick, and mouse, respectively. None of the FGF-8 isoforms exhibited activity to FGFR1b, 2b, 3b, but FGFR2c, 3c and FGFR4 can be activated by several FGF-8 isoforms. FGF-8 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration, and it is required for normal brain, eye, ear and limb development during embryogenesis. FGF-8 shows limited expression in the normal adult, but low levels are found in the reproductive and genitourinary tract, peripheral leukocytes and bone marrow hematopoietic cells. 
    
 
    
Product Properties
    
 
    

    

        

            

                

                
Synonyms
                
                

                
AIGF, AIGFKAL6, HBGF-8, FGF-8c
                
            
            

                

                
Accession
                
                

                
P37237
                
            
            

                

                
GeneID
                
                

                
14179
                
            
            

                

                
Source
                
                

                
E.coli-derived mouse FGF-8, Gln23-Arg268.
                
            
            

                

                
Molecular Weight
                
                

                
Approximately 28.1 kDa.
                
            
            

                

                
AA Sequence
                
                

                
QVRSAAQKRG PGAGNPADTL GQGHEDRPFG QRSRAGKNFT NPAPNYPEEG SKEQRDSVLP KVTQRHVREQ SLVTDQLSRR LIRTYQLYSR TSGKHVQVLA NKRINAMAED GDPFAKLIVE TDTFGSRVRV RGAETGLYIC MNKKGKLIAK SNGKGKDCVF TEIVLENNYT ALQNAKYEGW YMAFTRKGRP RKGSKTRQHQ REVHFMKRLP RGHHTTEQSL RFEFLNYPPF TRSLRGSQRT WAPEPR
                
            
            

                

                
Tag
                
                

                
None
                
            
            

                

                
Physical Appearance