Product Information
 


    

        

            

            
Product Name
            
            

            
Cat#
            
            

            
Size
            
            

            
Price（¥）
            
        
        

            

            
Recombinant Human Interleukin-13 (Human IL-13)
            
            

            
90112ES10
            
            

            
10μg
            
            

            
1855.00
            
        
        

            

            
90112ES60
            
            

            
100μg
            
            

            
13615.00
            
        
        

            

            
90112ES76
            
            

            
500μg
            
            

            
35395.00
            
        
    


 
Product Description
 
Interleukin-13 (IL-13) was first recognized for its effects on B cells and monocytes, where it upregulated class II expression, promoted IgE class switching and inhibited inflammatory cytokine production. IL-13 is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. Mature human IL-13 shares approximately 58% amino acid sequence identity with mouse and rat IL-13. It has become evident that IL-13 is a key mediator in the pathogenesis of allergic inflammation, and IL-13 is key proinflammatory cytokines in asthma. The cytokines interleukin IL-13 have pleiotropic effects on a variety of cell types and impact both pathologic changes and tissue remodeling.
 
Product Properties
 


    

        

            

            
Synonyms
            
            

            
BHR1interleukin-13, IL13, interleukin 13, MGC116786, NC30, P600
            
        
        

            

            
Accession
            
            

            
P35225
            
        
        

            

            
GeneID
            
            

            
3596
            
        
        

            

            
Source
            
            

            
E.coli-derived Human IL-13, Gly35-Asp146.
            
        
        

            

            
Molecular Weight
            
            

            
Approximately 12.5 kDa.
            
        
        

            

            
AA Sequence
            
            

            
GPVPPSTALR ELIEELVNIT QNQKAPLCNG SMVWSINLTA GMYCAALESL INVSGCSAIE KTQRMLSGFC PHKVSAGQFS SLHVRDTKIE VAQFVKDLLL HLKKLFREGR FN
            
        
        

            

            
Tag
            
            

            
None
            
        
        

            

            
Physical Appearance
            
            

            
Sterile Filtered White lyophilized (freeze-dried) powder.
            
        
        

            

            
Purity
            
            

            
> 97% by SDS-PAGE and HPLC analyses.
            
        
        

            

            
Biological Activity