SLC6A4 (Human) Recombinant Protein (Q01)
产品名称： SLC6A4 (Human) Recombinant Protein (Q01)
英文名称： SLC6A4 (Human) Recombinant Protein (Q01)
产品编号： H00006532-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human SLC6A4 partial ORF ( NP_001036, 181 a.a. - 252 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- AWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGIS
- Theoretical MW (kDa):
- 33.66
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 6532
- GeneBank Accession#:
- NM_001045
- Protein Accession#:
- NP_001036
- Gene Name:
- SLC6A4
- Gene Alias:
- 5-HTT,5HTT,HTT,OCD1,SERT,hSERT
- Gene Description:
- solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq
- Other Designations:
- 5-hydroxytryptamine transporter,5HT transporter,Na+/Cl- dependent serotonin transporter,serotonin transporter,sodium-dependent serotonin transporter,solute carrier family 6 member 4
- Related Disease
- Achievement
- Acute Disease
- Adolescent Psychology
- Agoraphobia
- Akathisia, Drug-Induced
- Alcohol Withdrawal Delirium
- Alcoholic Intoxication
- Alcoholism
- Alcohol-Related Disorders
- Alzheimer Disease
- Alzheimer disease
- Amphetamine-Related Disorders
- Amyloid Neuropathies, Familial
- Anorexia Nervosa
- Anoxemia
- Antisocial Personality Disorder
- Anxiety Disorders
- Appetite
- Aptitude