Beta-Amyloid [1-28] Antibody
产品名称: Beta-Amyloid [1-28] Antibody
英文名称: Beta-Amyloid [1-28] Antibody
产品编号: 250922
产品价格: null
产品产地: 美国
品牌商标: Abbiotec
更新时间: null
使用范围: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500
深圳市豪地华拓生物科技有限公司
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- 地址 : 深圳市南山创业路中兴城5栋518
- 邮编 : 518054
- 所在区域 : 广东
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- 邮箱 : order@otwobiotech.com
Beta-amyloid production results from cleavage in the extracellular domain of APP by the beta-secretase (BACE1) , which results in the production of the APP C-terminal fragment C99. This fragment is further cleaved by the gamma-secretase at residues 40-42 to produce beta-amyloid 40 and 42 peptides. Beta-amyloid aggregation and neuritic plaque formation are pathologic hallmarks of Alzheimer disease. This fragment is the amino terminus (1-28) of beta amyloid.