FITC标记的牛磺酸/β-氨基乙磺酸抗体
产品名称： FITC标记的牛磺酸/β-氨基乙磺酸抗体
英文名称： Anti-Taurine/FITC
产品编号： HZ-4560R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Taurine/FITC Conjugated antibody
FITC标记的牛磺酸/β-氨基乙磺酸抗体
| 产品编号 | bs-4560R-FITC |
| 英文名称 | Anti-Taurine/FITC |
| 中文名称 | FITC标记的牛磺酸/β-氨基乙磺酸抗体 |
| 别 名 | 2 aminoethanesulfonic acid; Taurine. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 产品类型 | 药物与化合物抗体 |
| 研究领域 | 心血管 细胞生物 免疫学 神经生物学 药物及化合物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Taurine |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated to Taurine |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Taurine is conjugated via its amino terminal group with the bile acids chenodeoxycholic acid and cholic acid to form the bile salts sodium taurochenodeoxycholate and sodium taurocholate. The low pKa (1.5) of taurine's sulfonic acid group ensures that this moiety is negatively charged in the pH ranges normally found in the intestinal tract and thus improves the surfactant properties of the cholic acid conjugate. Taurine has also been implicated in a wide array of other physiological phenomena including inhibitory neurotransmission, long-term potentiation in the striatum/hippocampus, membrane stabilization, feedback inhibition of neutrophil/macrophage respiratory bursts, adipose tissue regulation and calcium homeostasis. The evidence for these claims, when compared against that reported for taurine's role in bile acid synthesis and osmoregulation, is relatively poor. Premature born infants who lack the enzymes needed to convert cystathione to cysteine may become deficient in taurine. Thus, taurine is a dietary essential nutrient in these individuals. Many therapeutic applications of taurine have been investigated. Some conditions that taurine might be useful in treating include: cardiovascular diseases, hypercholesterolemia, epilepsy and other seizure disorders, macular degeneration, Alzheimer's disease, hepatic disorders, alcoholism, and cystic fibrosis. Recent studies show that taurine supplements taken by mice on a high-fat diet reduced their overall weight. Studies have yet to be done on the effect of taurine on obesity in humans. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
牛磺酸通过其氨基末端基团与胆汁酸鹅去氧胆酸和胆酸结合形成胆汁盐牛磺鹅去氧胆酸钠和牛磺胆酸钠。牛磺酸磺酸基的低pKa（1.5）保证了该部分在通常在肠道中发现的pH范围内带负电荷，从而提高了胆酸偶联物的表面活性剂性质。牛磺酸还牵涉到广泛的其他生理现象，包括抑制神经传递、纹状体/海马长时程增强、膜稳定、中性粒细胞/巨噬细胞呼吸爆发的反馈抑制、脂肪组织调节和钙化。M稳态。与牛磺酸在胆汁酸合成和渗透调节中的作用相比，这些说法的证据相对较差。早产儿缺乏胱天酮向半胱氨酸转化所需的酶可能会缺乏牛磺酸。因此牛磺酸是这些个体的膳食必需营养素。对牛磺酸的许多治疗应用进行了研究。牛磺酸可用于治疗的一些疾病包括：心血管疾病、高胆固醇血症、癫痫和其他癫痫发作、黄斑变性、阿尔茨海默病、肝病、酒精中毒和囊性纤维化。最近的研究表明，牛磺酸补充高脂肪饮食小鼠降低了他们的整体体重。牛磺酸对人类肥胖症的影响还有待研究。