GRK5 (C-term) Peptide
产品名称： GRK5 (C-term) Peptide
英文名称： GRK5 (C-term) Peptide
产品编号： P2090
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of GRK5.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to 561-590 amino acids at C-terminus of human GRK5.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Synucleins are a novel class of substrates for G protein-coupled receptor kinases.
Pronin AN, Morris AJ, Surguchov A, Benovic JL.J Biol Chem. 2000 Aug 25;275(34):26515-22.
- 2.
- Cross-talk between orphan nuclear hormone receptor RZRalpha and peroxisome proliferator-activated receptor alpha in regulation of the peroxisomal hydratase-dehydrogenase gene.
Winrow CJ, Capone JP, Rachubinski RA.J Biol Chem. 1998 Nov 20;273(47):31442-8.
- 3.
- Involvement of G protein-coupled receptor kinase 5 in homologous desensitization of the thyrotropin receptor.
Nagayama Y, Tanaka K, Hara T, Namba H, Yamashita S, Taniyama K, Niwa M.J Biol Chem. 1996 Apr 26;271(17):10143-8.
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with GRK5 polyclonal antibody (Cat # PAB4519) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . BC = breast carcinoma .
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- ELISA
- Entrez GeneID:
- 2869
- Protein Accession#:
- P34947
- Gene Name:
- GRK5
- Gene Alias:
- GPRK5
- Gene Description:
- G protein-coupled receptor kinase 5
- Omim ID:
- 600870
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). [provided by RefSeq
- Other Designations:
- -
- Gene Pathway