CDKL5 (C-term) Peptide
产品名称： CDKL5 (C-term) Peptide
英文名称： CDKL5 (C-term) Peptide
产品编号： P2421
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CDKL5.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human CDKL5.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Disruption of the serine/threonine kinase 9 gene causes severe X-linked infantile spasms and mental retardation.
Kalscheuer VM, Tao J, Donnelly A, Hollway G, Schwinger E, Kubart S, Menzel C, Hoeltzenbein M, Tommerup N, Eyre H, Harbord M, Haan E, Sutherland GR, Ropers HH, Gecz J.Am J Hum Genet. 2003 Jun;72(6):1401-11. Epub 2003 May 7.
- 2.
- Identification and characterization of a novel serine-threonine kinase gene from the Xp22 region.
Montini E, Andolfi G, Caruso A, Buchner G, Walpole SM, Mariani M, Consalez G, Trump D, Ballabio A, Franco B.Genomics. 1998 Aug 1;51(3):427-33.
- Applications
- Western Blot (Tissue lysate)
- The CDKL5 polyclonal antibody (Cat # PAB2814) is used in Western blot to detect STK9 in mouse lung tissue lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CDKL5 polyclonal antibody (Cat # PAB2814) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 6792
- Protein Accession#:
- NP_003150;O76039
- Gene Name:
- CDKL5
- Gene Alias:
- ISSX,STK9
- Gene Description:
- cyclin-dependent kinase-like 5
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of Ser/Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized. [provided by RefSeq
- Other Designations:
- OTTHUMP00000023002,OTTHUMP00000023003,serine/threonine kinase 9