BIRC5 polyclonal antibody
产品名称： BIRC5 polyclonal antibody
英文名称： BIRC5 polyclonal antibody
产品编号： PAB9714
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of BIRC5.
- Immunogen:
- A synthetic peptide corresponding to amino acids 129-142 of Human BIRC5.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation.
Kobayashi K, Hatano M, Otaki M, Ogasawara T, Tokuhisa T.Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1457-62.
- 2.
- Control of apoptosis and mitotic spindle checkpoint by survivin.
Li F, Ambrosini G, Chu EY, Plescia J, Tognin S, Marchisio PC, Altieri DC.Nature. 1998 Dec 10;396(6711):580-4.
- 3.
- A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma.
Ambrosini G, Adida C, Altieri DC.Nat Med. 1997 Aug;3(8):917-21.
- Entrez GeneID:
- 332
- Gene Name:
- BIRC5
- Gene Alias:
- API4,EPR-1
- Gene Description:
- baculoviral IAP repeat-containing 5
- Omim ID:
- 603352
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq
- Other Designations:
- apoptosis inhibitor 4,baculoviral IAP repeat-containing protein 5,survivin variant 3 alpha
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Carcinoma, Adenosquamous
- Carcinoma, Squamous Cell
- Carcinoma, Transitional Cell
- Cell Transformation, Neoplastic
- Colorectal Neoplasms
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Kidney Failure, Chronic
- Leukemia, chronic myeloid
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Leukemia, Myeloid, Acute
- Lung Neoplasms
- Lymphatic Metastasis
- Neoplasm Recurrence, Local
- Neoplasms, Second Primary
- Neovascularization, Pathologic
- Pancreatic Neoplasms