BBC3 polyclonal antibody
产品名称： BBC3 polyclonal antibody
英文名称： BBC3 polyclonal antibody
产品编号： PAB13106
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of BBC3.
- Immunogen:
- A synthetic peptide corresponding to N-terminus 14 amino acids of human BBC3.
- Host:
- Rabbit
- Reactivity:
- Human
- Specificity:
- This sequence is identical between a and b forms of the PUMA proteins. K-562 cell lysate can be used as a positive control and a band at approximately 23 KDa can be detected. antibody can also detect PUMA by immunohistochemistry at 10 ug/mL.
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (2-4 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals.
Han J, Flemington C, Houghton AB, Gu Z, Zambetti GP, Lutz RJ, Zhu L, Chittenden T.Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11318-23.
- 2.
- PUMA, a novel proapoptotic gene, is induced by p53.
Nakano K, Vousden KH.Mol Cell. 2001 Mar;7(3):683-94.
- 3.
- PUMA induces the rapid apoptosis of colorectal cancer cells.
Yu J, Zhang L, Hwang PM, Kinzler KW, Vogelstein B.Mol Cell. 2001 Mar;7(3):673-82.
- Gene Pathway