PRSS1 Pre-design Chimera RNAi
产品名称： PRSS1 Pre-design Chimera RNAi
英文名称： PRSS1 Pre-design Chimera RNAi
产品编号： H00005644-R01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Homo sapiens protease, serine, 1 (trypsin 1) (PRSS1), mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_002769
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 5644
- Gene Name:
- PRSS1
- Gene Alias:
- MGC120175,MGC149362,TRP1,TRY1,TRY4,TRYP1
- Gene Description:
- protease, serine, 1 (trypsin 1)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. [provided by RefSeq
- Other Designations:
- cationic trypsinogen,digestive zymogen,nonfunctional trypsin 1,protease, serine, 1,serine protease 1,trypsin I,trypsinogen 1,trypsinogen A
- Gene Pathway
- Related Disease
- Acute Disease
- Adenocarcinoma
- Calcinosis
- Chronic Disease
- Cystic Fibrosis
- Cystic fibrosis
- Diabetes Mellitus
- Exocrine Pancreatic Insufficiency
- Genetic Predisposition to Disease
- Hyperlipidemias
- Hyperparathyroidism, Primary
- Infant, Newborn, Diseases
- Pancreatic cancer
- Pancreatic Diseases
- Pancreatic Neoplasms
- Pancreatitis
- Pancreatitis, Alcoholic
- Pancreatitis, Chronic
- Recurrence