CTSD monoclonal antibody, clone CTD-19
产品名称： CTSD monoclonal antibody, clone CTD-19
英文名称： CTSD monoclonal antibody, clone CTD-19
产品编号： MAB7243
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against full length native CTSD.
- Immunogen:
- Native purified human CTSD.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- Recognizes cathepsin D (34 KDa and weaker band at 52 KDa) in immunoblotting. Does not react with bovine cathepsin D and B, or with human cathepsin types B, C, G or H.
- Form:
- Liquid
- Isotype:
- IgG2a
- Storage Buffer:
- In ascites (15 mM sodium azide)
- Storage Instruction:
- Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:1000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Differential expression of cathepsins B and D in testis and epididymis of adult rats.
Igdoura SA, Morales CR, Hermo L.J Histochem Cytochem. 1995 May;43(5):545-57.
- 2.
- A secreted glycoprotein induced by estrogen in human breast cancer cell lines.
Westley B, Rochefort H.Cell. 1980 Jun;20(2):353-62.
- Applications
- Application Image
- Western Blot (Cell lysate)
- enlarge
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- ELISA
- Entrez GeneID:
- 1509
- Gene Name:
- CTSD
- Gene Alias:
- CLN10,CPSD,MGC2311
- Gene Description:
- cathepsin D
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. [provided by RefSeq
- Other Designations:
- lysosomal aspartyl peptidase,lysosomal aspartyl protease
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Breast Neoplasms
- Cardiovascular Diseases
- Chronic Disease
- Cognition
- Cognition Disorders
- Creutzfeldt-Jakob Syndrome
- Dementia
- Dementia, Multi-Infarct
- Depressive Disorder
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Memory
- Mental Processes
- Metabolic Syndrome X
- Neoplasms