IL18 monoclonal antibody, clone SB116b1
产品名称： IL18 monoclonal antibody, clone SB116b1
英文名称： IL18 monoclonal antibody, clone SB116b1
产品编号： MAB8224
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant IL18.
- Immunogen:
- Recombinant protein corresponding to human IL33.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG2a
- Storage Buffer:
- In 100 mM BBS, pH 8.2
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- ELISA (1-5 ug/mL)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Differences in signaling pathways by IL-1beta and IL-18.
Lee JK, Kim SH, Lewis EC, Azam T, Reznikov LL, Dinarello CA.Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8815-20. Epub 2004 May 25.
- 2.
- Mechanisms of inhibition of collagen-induced arthritis by murine IL-18 binding protein.
Banda NK, Vondracek A, Kraus D, Dinarello CA, Kim SH, Bendele A, Senaldi G, Arend WP.J Immunol. 2003 Feb 15;170(4):2100-5.
- 3.
- Interleukin-18/interleukin-18 binding protein signaling modulates atherosclerotic lesion development and stability.
Mallat Z, Corbaz A, Scoazec A, Graber P, Alouani S, Esposito B, Humbert Y, Chvatchko Y, Tedgui A.Circ Res. 2001 Sep 28;89(7):E41-5.
- Application Image
- ELISA
- Entrez GeneID:
- 3606
- Gene Name:
- IL18
- Gene Alias:
- IGIF,IL-18,IL-1g,IL1F4,MGC12320
- Gene Description:
- interleukin 18 (interferon-gamma-inducing factor)
- Omim ID:
- 600953
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. [provided by RefSeq
- Other Designations:
- IL-1 gamma,interferon-gamma-inducing factor,interleukin 18,interleukin-1 gamma,interleukin-18
- Gene Pathway
- Related Disease
- Abortion, Habitual
- Abortion, Spontaneous
- Acute Lung Injury
- Adenocarcinoma
- Aggressive Periodontitis
- Alzheimer Disease
- Alzheimer disease
- Arthritis
- Arthritis, Juvenile Rheumatoid
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Atherosclerosis
- Atherosclerosis
- Atrial Fibrillation
- Autoimmune Diseases
- Behcet Syndrome
- Brain Ischemia
- Breast cancer