ITGAV (Human) Recombinant Protein
产品名称: ITGAV (Human) Recombinant Protein
英文名称: ITGAV (Human) Recombinant Protein
产品编号: H00003685-G01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- Specification
- Product Description:
- Human ITGAV full-length ORF (NP_002201.1) recombinant protein without tag.
- Sequence:
- MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSQMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET
- Theoretical MW (kDa):
- 116
- Form:
- Liquid
- Preparation Method:
- in vitro wheat germ expression system with proprietary liposome technology
- Storage Buffer:
- 25 mM Tris-HCl of pH8.0 containing 2% glycerol.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Note:
- Best use within three months from the date of receipt of this protein.
- Publication Reference
- 1.
- Production and partial purification of membrane proteins using a liposome-supplemented wheat cell-free translation system.
Nozawa A, Ogasawara T, Matsunaga S, Iwasaki T, Sawasaki T, Endo Y. BMC Biotechnol. 2011 Apr 11;11:35.
- Application Image
- Antibody Production
- Functional Study
- Compound Screening
- Entrez GeneID:
- 3685
- GeneBank Accession#:
- NM_002210.2
- Protein Accession#:
- NP_002201.1
- Gene Name:
- ITGAV
- Gene Alias:
- CD51,DKFZp686A08142,MSK8,VNRA
- Gene Description:
- integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
- Omim ID:
- 193210
- Gene Ontology:
- Hyperlink
- Gene Summary:
- ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq
- Other Designations:
- Integrin, alpha-V (vitronectin receptor, alpha polypeptide),antigen identified by monoclonal antibody L230,integrin alpha-V
- Related Disease
- Anemia, Sickle Cell
- Anemia, sickle cell
- Arthritis, Rheumatoid
- Breast cancer
- Breast Neoplasms
- Carcinoma, Hepatocellular
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Hepatitis B, Chronic
- Ovarian Neoplasms
- Priapism
- Thalassemia
- Thalassemia
- Tobacco Use Disorder