DDR1 polyclonal antibody
产品名称： DDR1 polyclonal antibody
英文名称： DDR1 polyclonal antibody
产品编号： PAB16328
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of DDR1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to human DDR1.
- Host:
- Rabbit
- Reactivity:
- Human
- Specificity:
- N-terminal region of human.
- Form:
- Liquid
- Purification:
- Immunoaffinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS (0.1% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (15-20 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 780
- Protein Accession#:
- Q08345
- Gene Name:
- DDR1
- Gene Alias:
- CAK,CD167,DDR,EDDR1,MCK10,NEP,NTRK4,PTK3,PTK3A,RTK6,TRKE
- Gene Description:
- discoidin domain receptor tyrosine kinase 1
- Omim ID:
- 600408
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. This gene is located on chromosome 6p21.3 in proximity to several HLA class I genes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq
- Other Designations:
- OTTHUMP00000029343,OTTHUMP00000029344,OTTHUMP00000029345,OTTHUMP00000029346,OTTHUMP00000029347,PTK3A protein tyrosine kinase 3A,cell adhesion kinase,discoidin domain receptor DDR1d,discoidin domain receptor family, member 1,discoidin receptor tyrosine kin