PRDX1 monoclonal antibody, clone AT1D8
产品名称： PRDX1 monoclonal antibody, clone AT1D8
英文名称： PRDX1 monoclonal antibody, clone AT1D8
产品编号： MAB7559
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant PRDX1.
- Immunogen:
- Recombinant protein corresponding to amino acids 1-199 of human PRDX1.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This antibody reacts with human PRDX1.
- Form:
- Liquid
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- HDAC6 is a specific deacetylase of peroxiredoxins and is involved in redox regulation.
Parmigiani RB, Xu WS, Venta-Perez G, Erdjument-Bromage H, Yaneva M, Tempst P, Marks PA.Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9633-8. Epub 2008 Jul 7.
- 2.
- Up-regulation of peroxiredoxin 1 in lung cancer and its implication as a prognostic and therapeutic target.
Kim JH, Bogner PN, Baek SH, Ramnath N, Liang P, Kim HR, Andrews C, Park YM.Clin Cancer Res. 2008 Apr 15;14(8):2326-33.
- 3.
- Human peroxiredoxin PrxI is an orthologue of yeast Tsa1, capable of suppressing genome instability in Saccharomyces cerevisiae.
Iraqui I, Faye G, Ragu S, Masurel-Heneman A, Kolodner RD, Huang ME.Cancer Res. 2008 Feb 15;68(4):1055-63.
- Applications
- Western Blot (Cell lysate)
- Cell lysates of HeLa (40 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with PRDX1 monoclonal antibody, clone AT1D8 (Cat # MAB7559) (1 : 1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
- Entrez GeneID:
- 5052
- Protein Accession#:
- NP_002565
- Gene Name:
- PRDX1
- Gene Alias:
- MSP23,NKEFA,PAG,PAGA,PAGB,PRX1,PRXI,TDPX2
- Gene Description:
- peroxiredoxin 1
- Omim ID:
- 176763
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000009234,natural killer-enhancing factor A,proliferation-associated gene A,thioredoxin-dependent peroxide reductase 2
- Related Disease