CYP3A7 (Human) Recombinant Protein (Q01)
产品名称: CYP3A7 (Human) Recombinant Protein (Q01)
英文名称: CYP3A7 (Human) Recombinant Protein (Q01)
产品编号: H00001551-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human CYP3A7 partial ORF ( NP_000756, 28 a.a. - 117 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- RTHGLFKKLGIPGPTPLPFLGNALSFRKGYWTFDMECYKKYRKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKNA
- Theoretical MW (kDa):
- 35.64
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 1551
- GeneBank Accession#:
- NM_000765
- Protein Accession#:
- NP_000756
- Gene Name:
- CYP3A7
- Gene Alias:
- CP37,P450-HFLA
- Gene Description:
- cytochrome P450, family 3, subfamily A, polypeptide 7
- Omim ID:
- 605340
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced. [provided by RefSeq
- Other Designations:
- aryl hydrocarbon hydroxylase,cytochrome P450, subfamily IIIA, polypeptide 7,flavoprotein-linked monooxygenase,microsomal monooxygenase,xenobiotic monooxygenase
- Related Disease
- Breast cancer
- Breast Neoplasms
- Cleft Lip
- Cleft Palate
- Genetic Predisposition to Disease
- HIV Infections
- Kidney Failure, Chronic
- Lung Neoplasms
- Neoplasms, Glandular and Epithelial
- Osteoporosis, Postmenopausal
- Ovarian cancer
- Ovarian Neoplasms
- Polycystic Ovary Syndrome
- Prostatic Neoplasms
- Pulmonary Disease, Chronic Obstructive
- Urinary Bladder Neoplasms
- Werner syndrome