PNPO monoclonal antibody, clone AT2C7
产品名称： PNPO monoclonal antibody, clone AT2C7
英文名称： PNPO monoclonal antibody, clone AT2C7
产品编号： MAB11110
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant PNPO.
- Immunogen:
- Recombinant protein corresponding to amino acids 57-261 of human PNPO.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Concentration:
- 1 mg/mL
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:5000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Cell lysate)
- Cell extracts of HepG2 (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with PNPO monoclonal antibody, clone AT2C7 (Cat # MAB11110). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
Lane 1: 1:5000
Lane 2: 1:1000
Lane 3: 1:500
- Entrez GeneID:
- 55163
- Protein Accession#:
- NP_060599
- Gene Name:
- PNPO
- Gene Alias:
- FLJ10535,PDXPO
- Gene Description:
- pyridoxamine 5'-phosphate oxidase
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq
- Other Designations:
- pyridoxal 5'-phosphate synthase,pyridoxine 5'-phosphate oxidase
- Gene Pathway
- Related Disease