PDGFRB (phospho Y740) polyclonal antibody
产品名称： PDGFRB (phospho Y740) polyclonal antibody
英文名称： PDGFRB (phospho Y740) polyclonal antibody
产品编号： PAB4913
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of PDGFRB.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y740 of human PDGFRB.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Autoinhibition of the platelet-derived growth factor beta-receptor tyrosine kinase by its C-terminal tail.
Chiara F, Bishayee S, Heldin CH, Demoulin JB.J Biol Chem. 2004 May 7;279(19):19732-8. Epub 2004 Mar 2.
- 2.
- Positive and negative regulatory roles of the WW-like domain in TEL-PDGFbetaR transformation.
Chen J, Williams IR, Kutok JL, Duclos N, Anastasiadou E, Masters SC, Fu H, Gilliland DG.Blood. 2004 Jul 15;104(2):535-42. Epub 2004 Mar 30.
- 3.
- Expression of ligand-activated KIT and platelet-derived growth factor receptor beta tyrosine kinase receptors in synovial sarcoma.
Tamborini E, Bonadiman L, Greco A, Gronchi A, Riva C, Bertulli R, Casali PG, Pierotti MA, Pilotti S.Clin Cancer Res. 2004 Feb 1;10(3):938-43.
- Entrez GeneID:
- 5159
- Protein Accession#:
- NP_002600;P09619
- Gene Name:
- PDGFRB
- Gene Alias:
- CD140B,JTK12,PDGF-R-beta,PDGFR,PDGFR1
- Gene Description:
- platelet-derived growth factor receptor, beta polypeptide
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq
- Other Designations:
- beta platelet-derived growth factor receptor,platelet-derived growth factor receptor beta,soluble PDGFRb variant 1
- Interactome
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- Acute Disease
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- Diabetes Mellitus, Type 2
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- Edema
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