GCNT1 polyclonal antibody
产品名称： GCNT1 polyclonal antibody
英文名称： GCNT1 polyclonal antibody
产品编号： PAB4301
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of GCNT1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to internal region of human GCNT1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Genomic organization of core 2 and I branching beta-1,6-N-acetylglucosaminyltransferases. Implication for evolution of the beta-1,6-N-acetylglucosaminyltransferase gene family.
Bierhuizen MF, Maemura K, Kudo S, Fukuda M.Glycobiology. 1995 Jun;5(4):417-25.
- 2.
- Expression cloning of a cDNA encoding UDP-GlcNAc:Gal beta 1-3-GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase by gene transfer into CHO cells expressing polyoma large tumor antigen.
Bierhuizen MF, Fukuda M.Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):9326-330.
- Applications
- Western Blot (Tissue lysate)
- The GCNT1 polyclonal antibody (Cat # PAB4301) is used in Western blot to detect GCNT1 in mouse kidney tissue lysate .
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with GCNT1 polyclonal antibody (Cat # PAB4301) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . HC = hepatocarcinoma .
- Entrez GeneID:
- 2650
- Protein Accession#:
- G6NT_HUMAN
- Gene Name:
- GCNT1
- Gene Alias:
- C2GNT,C2GNT-L,C2GNT1,G6NT,MGC126335,MGC126336,NACGT2,NAGCT2
- Gene Description:
- glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
- Omim ID:
- 600391
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the beta-1,6-N-acetylglucosaminyltransferase gene family. It is essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures and the core 2 O-glycan branch. The gene coding this enzyme was originally mapped to 9q21, but was later localized to 9q13. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
- Other Designations:
- OTTHUMP00000021502,beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase,beta-1,6-N-acetylglucosaminyltransferase,core 2 GnT,core 2 beta-1,6-N-acetylglucosaminyltransferase I,core 2 branching enzyme
- Gene Pathway