NR0B2 (Human) Recombinant Protein (P01)
产品名称： NR0B2 (Human) Recombinant Protein (P01)
英文名称： NR0B2 (Human) Recombinant Protein (P01)
产品编号： H00008431-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human NR0B2 full-length ORF ( AAH30207, 1 a.a. - 257 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MSTSQPGACPCQGAASRPAILYALLSSSLKAVPRPRSRCLCRQHRPVQLCAPHRTCREALDVLAKTVAFLRNLPSFWQLPPQDQRRLLQGCWGPLFLLGLAQDAVTFEVAEAPVPSILKKILLEEPSSSGGSGQLPDRPQPSLAAVQWLQCCLESFWSLELSPKEYACLKGTILFNPDVPGLQAASHIGHLQQEAHWVLCEVLEPWCPAAQGRLTRVLLTASTLKSIPTSLLGDLFFRPIIGDVDIAGLLGDMLLLR
- Theoretical MW (kDa):
- 54.01
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 8431
- GeneBank Accession#:
- BC030207
- Protein Accession#:
- AAH30207
- Gene Name:
- NR0B2
- Gene Alias:
- FLJ17090,SHP,SHP1
- Gene Description:
- nuclear receptor subfamily 0, group B, member 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq
- Other Designations:
- OTTHUMP00000004414,orphan nuclear receptor SHP,short heterodimer partner,small heterodimer partner
- Related Disease
- Asthma
- Asthma
- Birth Weight
- Body Weight
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Disease Progression
- Disease Susceptibility
- Genetic Predisposition to Disease
- HIV Infections
- Hyperinsulinism
- Liver Cirrhosis
- Obesity
- Obesity
- Obesity, Morbid
- Ovarian Failure, Premature
- Polycystic Ovary Syndrome
- Puberty, Delayed
- Puberty, Precocious