FITC标记的多药耐药相关蛋白4抗体
产品名称： FITC标记的多药耐药相关蛋白4抗体
英文名称： Anti-MRP4/ABCC4/FITC
产品编号： HZ-1422R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-MRP4/ABCC4/FITC Conjugated antibody
FITC标记的多药耐药相关蛋白4抗体
| 英文名称 | Anti-MRP4/ABCC4/FITC |
| 中文名称 | FITC标记的多药耐药相关蛋白4抗体 |
| 别 名 | ABCC 4; ABCC4; ATP binding cassette sub family C (CFTR/MRP) member 4; ATP binding cassette sub family C member 4; bA464I2.1 (ATP binding cassette, sub-family C (CFTR/MRP) member 4); bA464I2.1; Canalicular multispecific organic anion transporter; Canalicular multispecific organic anion transporter ABC superfamily; EST170205; MOAT B; MOATB; MRP 4; MRP/cMOAT related ABC transporter; Multi specific organic anion transporter B; Multidrug resistance associated protein 4; OTTHUMP00000018560; MRP4_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Guinea Pig, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 149kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MRP4 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq, Jul 2008]. Function: May be an organic anion pump relevant to cellular detoxification. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Widely expressed, with particularly high levels in prostate, but is barely detectable in liver. Similarity: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. Contains 2 ABC transmembrane type-1 domains. Contains 2 ABC transporter domains. Database links: Entrez Gene: 10257 Human Entrez Gene: 239273 Mouse Omim: 605250 Human SwissProt: O15439 Human Unigene: 508423 Human Unigene: 40537 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
由该基因编码的蛋白质是ATP结合盒（ABC）转运蛋白超家族的成员。ABC蛋白通过胞外膜和胞内膜运输各种分子。ABC基因分为七个不同亚家族（ABC1、MDR/TAP、MRP、ALD、OABP、GCN20、White）。该蛋白是MRP亚家族成员，参与多药耐药。该蛋白的具体功能尚未确定；然而，该蛋白可能作为其底物有机阴离子的泵在细胞解毒中发挥作用。选择性剪接导致多个剪接变异体编码不同的亚型。[ RefSeq，JUL 2008 ]提供。